Cephalopods have more connective tissue and a greater amount of collagen in their bodies than other types of fish or shellfish. Squid and cuttlefish are either seared or grilled very briefly over high heat, or they are simmered at a low temperature for a long time to soften the collagen. (Otherwise their texture is tough and rubbery.) Octopus must always be cooked for a long period of time to tenderize the flesh.