The synergy in umami sensation is a true pairing principle based on solid science and is a universal trait, in contrast to the traditional pairing hypothesis for different types of foodstuffs, which has been shown to be dependent on food culture and adaptation. Cuisines around the world use universal umami synergy and pairing of glutamate and nucleotides in many traditional and innovative dishes. There are a few raw ingredients that can provide umami synergy on their own (sun-ripened tomatoes and nori used for sushi are two prominent examples).
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